If you've been diagnosed with advanced ovarian cancer, HRD testing can help your healthcare team identify appropriate treatments for you.

What To Expect

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An HRD test must be performed in a clinical setting. Testing will include taking a tumor tissue sample, during surgery or via a biopsy. Your healthcare team may be able to use tissue from the original biopsy used in your diagnosis. You may not need an additional procedure.

The first step is asking your doctor about getting an HRD test. They can order one for you.

When to Get an HRD Test

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Ideally, you should talk to your doctor about getting tested as soon as possible after diagnosis. But if your care team hasn’t discussed HRD testing, you may still have options. Everyone’s experience with ovarian cancer is different.

You can use our Doctor Discussion Guide to start a conversation with your healthcare team. They can let you know if your tumor was already tested for HRD. If you haven’t been tested, your team can provide guidance on testing recommendations and next steps.

An HRD test will also identify BRCA gene mutations, which can inform treatment options and indicate your risk of developing other cancers. If you have already been tested for BRCA and are BRCA-negative,* you could still test positive for HRD, as BRCA mutations only account for half of HRD-positive tumors.

Even if you have already been tested for BRCA and are BRCA-negative, you should still talk to your doctor about HRD testing. You can learn more about BRCA at beBRCAware.com.

Determining the Cost of HRD Testing

If you have been diagnosed with advanced ovarian cancer, your healthcare team can help you understand the cost of HRD testing and talk to you about your options.  

So, What Happens Next?

Following the test, your healthcare team will share the results, which will help determine next steps. The next steps may include:  

Surgery

Chemotherapy

Targeted Therapy

If your tumor tests positive for HRD, your doctor might prescribe a targeted treatment called a PARP inhibitor.

Learn more about a PARP inhibitor for certain types of advanced or recurrent ovarian cancer

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Knowing your tumor’s HRD status after diagnosis can help you and your doctor identify the most appropriate treatments for you. If you’ve been diagnosed with advanced ovarian cancer, you should talk to your doctor about getting an HRD test because it could directly impact your treatment plan.

*A negative result can be reassuring, but it’s important to understand what was tested—and what may still be unknown. A genetic counselor can help explain what it means for you and your family.